NSC 228155

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2955

CAS [113104-25-9]

MF C11H6N4O4S
MW 290.25

Purity: 98%
Soluble in DMSO

NSC 228155

Description

EGFR activator. Furthermore, NSC 228155 was identified as a potent inhibitor of KIX-KID interaction with an IC50 value of 0.36 µM.

F Xie et al. Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5371-5.

V Sakanyan et al. Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells. Sci Rep. 2014 Feb 5;4:3977.

Sakanyan V, et al. Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1. Sci Rep. 2016 Feb 17;6:21088.

Cell Signaling & Oncology EGFR JAK-STAT RTK class I; EC 2.7.10.1

EGFR tyrosine kinase activator; Inhibitor of KIX-KID interaction

Chemical name

2-(7-Nitrobenzo[c][1,2,5]oxadiazol-4-ylthio)pyridine 1-oxide

Parent CAS No.

[113104-25-9]

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4074	AZ5104	EGFR inhibitor	Recently added	Inquire

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