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LIT-927
- Soluble in 0.1N NaOH(aq) and DMSO
- MF: C17H13ClN2O3
- MW: 328.75
Description
LIT-927 is a selective, locally and orally active CXCL12 neutraligand (Ki value of 267 nM). Moreover, LIT-927 shows an anti-inflammatory effect in a murine model of allergic airway hypereosinophilia.
More Information
| Parent CAS No. | 2172879-52-4 |
|---|---|
| Chemical Name | 4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one |
| SMILES | C1C=C(C2=NC(=O)NC(C3C=C(OC)C(O)=CC=3)=C2)C=CC=1Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C17H13ClN2O3/c1-23-16-8-11(4-7-15(16)21)14-9-13(19-17(22)20-14)10-2-5-12(18)6-3-10/h2-9,21H,1H3,(H,19,20,22) |
| InChiKey | BYYRNPIGDRRGLJ-UHFFFAOYSA-N |
| CID | 137287575 |
| Short Description | CXCL12 neutraligand |
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