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Axon 2734
CAS [1190221-43-2]
MF C21H17ClN2O6MW 428.82
TM5441 is an orally active PAI-1 inhibitor, which protects mice against L-NAME–induced vascular pathologies, including hypertension, fibrosis, and vascular senescence. TM5441 is a derivative of PAI-1 inhibitor TM5275 (Axon 2344), however showed better pharmacokinetics and volume of distribution.
KEYWORDS: TM 5441 | supplier | PAI-1 inhibitor | TM-5441 | TM5441 | CAS [1190221-43-2] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | Inhibitor | Enzymes | L-NAME
5-Chloro-2-(2-(2-(3-(furan-3-yl)phenylamino)-2-oxoethoxy)acetamido)benzoic acid
[1190221-43-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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