TM 5441

Based on 8 reference(s) in Google Scholar 8 10 8

Axon 2734

CAS [1190221-43-2]

MF C21H17ClN2O6
MW 428.82

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO

TM 5441


TM5441 is an orally active PAI-1 inhibitor, which protects mice against L-NAME–induced vascular pathologies, including hypertension, fibrosis, and vascular senescence. TM5441 is a derivative of PAI-1 inhibitor TM5275 (Axon 2344), however showed better pharmacokinetics and volume of distribution.

KEYWORDS: TM 5441 | supplier | PAI-1 inhibitor | TM-5441 | TM5441 | CAS [1190221-43-2] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | Inhibitor | Enzymes | L-NAME

Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...