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Axon 2602
CAS [301353-96-8]
MF C21H18Br2N2OMW 474.19
Orally bioavailable and brain penetrant proneurogenic and neuroprotective compound that activates NAMPT (nicotinamide phosphoribosyltransferase). P7C3 exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis, and improves cognitive function in aged rats and increases neuronal survival in mouse models of Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS).
KEYWORDS: P7C3 | supplier | NAMPT activator | CAS [301353-96-8] | Nicotinamide D-ribonucleotide | nicotinamide phosphoribosyltransferase | orally bioavailable | brain penetrant | Parkinson's | amyotrophic lateral sclerosis | ALS | proneurogenic | neuroprotective | antidepressant | neurogenesis | cognitive function | neuronal survival
1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol
[301353-96-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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