Apilimod mesylate - STA 5326 mesylate

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Axon 2500

CAS [870087-36-8]

MF C23H26N6O2.2CH4O3S
MW 610.70

  • Purity: 98%
  • Soluble in water and DMSO

Apilimod mesylate

Description

Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases. Blocks the translocation of c-Rel, a member of the Rel/NF-κB family of transcription factors, to the nucleus without affecting the translocation of the other NF-κB family members. 
Water soluble dimesylate salt of Axon 1369.

Note: This item is currently suspended due to the request of the developer. You might request a quotation for contract research synthesis. Please contact us for conditions and more detailed information.

KEYWORDS: Apilimod mesylate | supplier | IL-12/23 inhibitor | STA 5326 mesylate | STA5326 | CAS [870087-36-8] | [541550-19-0] | Interleukin | IL-12 | IL-23 | autoimmune | inflammation | translocation | c-Rel | NF-κB | transcription factor

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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