Hulseberg, C. E., Fénéant, L., Szymańska-de Wijs, K. M., Kessler, N. P., Nelson, E. A., Shoemaker, C. J., ... & White, J. M. Arbidol and other low-molecular-weight drugs that inhibit Lassa and Ebola viruses. Journal of virology, 2019, 93(8).
https://jvi.asm.org/content/93/8/e02185-18.full

Min, S. H., Suzuki, A., Weaver, L., Guzman, J., Chung, Y., Jin, H., ... & Seeholzer, S. H. PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice. Molecular and cellular biology, 2019. 39(21), e00158-19.
https://mcb.asm.org/content/39/21/e00158-19.full

Isobe, Y., Nigorikawa, K., Tsurumi, G., Takemasu, S., Takasuga, S., Kofuji, S., & Hazeki, K. PIKfyve accelerates phagosome acidification through activation of TRPML1 while arrests aberrant vacuolation independent of the Ca2+ channel. The Journal of Biochemistry, 2019, 165(1), 75-84.
https://academic.oup.com/jb/article-abstract/165/1/75/5122774

Shi, Y., Lin, S., Staats, K. A., Li, Y., Chang, W. H., Hung, S. T., ... & Wen, X. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons. Nature medicine, 2018, 24(3), 313.
https://www.nature.com/articles/nm.4490.pdf?origin=ppub 

Wallner, F. K., Hopkins, M. H., Woodworth, N., Bark, T. L., Olofsson, P., & Tilevik, A. Correlation and cluster analysis of immunomodulatory drugs based on cytokine profiles. Pharmacological Research, 2018, 128, 244-251.
https://www.sciencedirect.com/science/article/pii/S1043661817311611  

*Apilimod dimesylate purchased from Axon Medchem

Sbrissa, D., Naisan, G., Ikonomov, O. C., & Shisheva, A. Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns (3, 5) P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation. PloS one, 2018, 13(9), e0204532.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204532

Ikonomov, O. C., Altankov, G., Sbrissa, D., & Shisheva, A. PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation. Toxicology and applied pharmacology, 2018, 356, 151-158.
https://www.sciencedirect.com/science/article/pii/S0041008X18303582

2017
Gao, Q. (2017). Regulation of Lysosomal Adaptation to Nutrient Starvation by Lysosomal TRPML1 and PIKfyve (Doctoral dissertation).
https://deepblue.lib.umich.edu/handle/2027.42/138614

Tilevik, A. (2017). Evaluation of clustering methods for analyzing drug cytokine profiles.
https://www.diva-portal.org/smash/record.jsf?pid=diva2:1145108
*Apilimod dimesylate used in this study was obtained from Axon Medchem

Tronchere, H., Cinato, M., Timotin, A., Guitou, L., Villedieu, C., Thibault, H., ... & Kunduzova, O. Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice. EMBO molecular medicine, 2017,  9(6), 770-785.
https://www.embopress.org/doi/full/10.15252/emmm.201607096

Wallner, F. K., Hopkins, M. H., Lindvall, T., Olofsson, P., & Tilevik, A. Cytokine correlation analysis based on drug perturbation. Cytokine, 2017, 90, 73-79.
https://www.sciencedirect.com/science/article/pii/S1043466616305555

Nelson, E. A., Dyall, J., Hoenen, T., Barnes, A. B., Zhou, H., Liang, J. Y., ... & Morris, P. J. The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection. PLoS neglected tropical diseases, 2017, 11(4), e0005540.
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005540&rev=1

Morris, P. J., Moore, C., & Thomas, C. J. Apilimod. IUCrData, 2017, 2(5), x170693.
https://scripts.iucr.org/cgi-bin/paper?zl4016

Sahoo, N., Gu, M., Zhang, X., Raval, N., Yang, J., Bekier, M., ... & Samie, M. Gastric acid secretion from parietal cells is mediated by a Ca2+ efflux channel in the tubulovesicle. Developmental cell, 2017, 41(3), 262-273.
https://www.sciencedirect.com/science/article/pii/S1534580717302964

Mironova, Y. A., Lenk, G. M., Lin, J. P., Lee, S. J., Twiss, J. L., Vaccari, I., ... & Shrager, P. (2016). PI (3, 5) P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms. Elife, 2017,  5, e13023.
https://elifesciences.org/articles/13023

2016
Krishna, S., Palm, W., Lee, Y., Yang, W., Bandyopadhyay, U., Xu, H., ... & Overholtzer, M. PIKfyve regulates vacuole maturation and nutrient recovery following engulfment. Developmental cell, 2016, 38(5), 536-547.
https://www.sciencedirect.com/science/article/pii/S1534580716305524

Krishna, S., Palm, W., Lee, Y., Yang, W., Bandyopadhyay, U., Xu, H., ... & Overholtzer, M. PIKfyve regulates vacuole maturation and nutrient recovery following engulfment. Developmental cell, 2016, 38(5), 536-547.
https://www.sciencedirect.com/science/article/pii/S1534580717302964

2015
Weaver, J. R., Nadler, J. L., & Taylor-Fishwick, D. A. Interleukin-12 (IL-12)/STAT4 axis is an important element for β-Cell dysfunction induced by inflammatory cytokines. PLoS One, 2015, 10(11), e0142735.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142735

Hong, N. H., Qi, A., & Weaver, A. M. PI (3, 5) P2 controls endosomal branched actin dynamics by regulating cortactin–actin interactions. Journal of Cell Biology, 2015, 210(5), 753-769.
https://rupress.org/jcb/article/210/5/753/38281/PI-3-5-P2-controls-endosomal-branched-actin

2013
Baird, A. M., Dockry, É., Daly, A., Stack, E., Doherty, D. G., O'Byrne, K. J., & Gray, S. G. IL-23R is epigenetically regulated and modulated by chemotherapy in non-small cell lung cancer. Frontiers in oncology, 2013, 3, 162.
https://www.frontiersin.org/articles/10.3389/fonc.2013.00162/full