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LM-2-27A

Name: LM-2-27A
SKU: 4289

Axon 4289

CAS: N.A.

Purity: 99%

Soluble in DMSO

MF: C22H21IN6O2S2
MW: 592.48

Description

LM-2-27A is a PIKfyve modulator with a Kd value of 34 nM. LM-2-27A displayed high efficacy at improving GCase activity at 10 µM.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

PIKfyve

Parent CAS No.	N.A.
Chemical Name	(4-Iodophenyl)(6-(6-ethoxy-1,3-benzothiazol-2-ylthio)-4-morpholino-1,3,5-triazin-2-yl)amine
MFCD	N.A.
Short Description	PIKfyve modulator

LM-2-27A PIKfyve modulator LM 2-27A LM2-27A CAS N.A. Axon Medchem Axon 4289 Phosphatidylinositol PIKfyve Modulator Enzymes Gaucher’s disease Lysosomal storage disease Parkinson’s disease Supplier Vendor

References

WC Hou et al. A PIKfyve modulator combined with an integrated stress response inhibitor to treat lysosomal storage diseases. Proc Natl Acad Sci USA. 2024 Aug 20;121(34):e2320257121.

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LM-2-27A

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