FDI 6 - NCGC 00099374

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2384

CAS [313380-27-7]

MF C19H11F4N3OS2
MW 437.43

  • Purity: 99%
  • Soluble in DMSO



Inhibitor of the Forkhead box protein M1 transcription factor (IC50 value 22.5 µM for inhibiting FOXM1-DNA binding). FDI6 displaces ​FOXM1 from genomic targets in MCF-7 breast cancer cells, and induces concomitant transcriptional downregulation. FDI-6 is inactive against the proteasome, and concordance between its biophysical IC50 and cellular GI50 values (22.5 μM and 18.0 μM, respectively) suggests it does not suffer from the off-target effects of ​thiostrepton.
Size Unit Price Stock
10 mg €99.00 In Stock
50 mg €295.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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