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STL001

Axon 4051
CAS:  3047493-70-6
Purity:  99%
  • Soluble in DMSO
  • MF:  C27H23N7O4
  • MW:  509.52

Description

STL001 is a FOXM1 inhibitor and exhibits selectivity toward suppressing FOXM1-controlled regulatory pathways. STL001 preserves the mode of action of STL427944 (Axon 4050), but is up to 50 times more efficient in reducing FOXM1 activity in a variety of solid cancers.

More Information

Parent CAS No. 3047493-70-6
Chemical Name 3-(1-(4-Morpholino-6-(phenylamino)-1,3,5-triazin-2-yl)-1H-pyrazol-3-yl)phenyl furan-2-carboxylate
SMILES C1(N2CCOCC2)N=C(NC2C=CC=CC=2)N=C(N2N=C(C3C=CC=C(OC(=O)C4OC=CC=4)C=3)C=C2)N=1
MFCD N.A.
InChi InChI=1S/C27H23N7O4/c35-24(23-10-5-15-37-23)38-21-9-4-6-19(18-21)22-11-12-34(32-22)27-30-25(28-20-7-2-1-3-8-20)29-26(31-27)33-13-16-36-17-14-33/h1-12,15,18H,13-14,16-17H2,(H,28,29,30,31)
InChiKey AAWXZSFTAZAKCO-UHFFFAOYSA-N
CID 171713969
Short Description FOXM1 inhibitor

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