SC 144 hydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2324

CAS [917497-70-2]

MF C16H111FN6O.HCl
MW 358.76

  • Purity: 99%
  • Soluble in DMSO

SC 144 hydrochloride

Description

The first-in-class small-molecule gp130 inhibitor with oral activity in ovarian cancer (IC50 values 0.43-0.95 µM for a range of human ovarian cancer cell lines). SC144 binds gp130, induces gp130 phosphorylation and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.
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Size Unit Price Stock
10 mg €135.00 In Stock
50 mg €535.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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