SC 144 hydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2324

CAS [917497-70-2]

MF C16H111FN6O.HCl
MW 358.76

  • Purity: 99%
  • Soluble in DMSO

SC 144 hydrochloride


The first-in-class small-molecule gp130 inhibitor with oral activity in ovarian cancer (IC50 values 0.43-0.95 µM for a range of human ovarian cancer cell lines). SC144 binds gp130, induces gp130 phosphorylation and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.
Size Unit Price Stock
10 mg €130.00 In Stock
50 mg €490.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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