Bizine

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2306

CAS [N.A.]

MF C18H23N3O.HCl
MW 333.86

  • Purity: 98%
  • Soluble in water and DMSO

Bizine

Description

Potent LSD1 inhibitor in vitro and selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2 with Ki(inact) values 0.059 μM, 2.6 μM, 6.5 μM, and ca 11 μM for LSD1, MAO-A, MAO-B, and LSD2 respectively. Bizine was found to be effective at modulating bulk histone methylation in cancer cells. Moreover, neurons exposed to oxidative stress were protected by the presence of bizine, suggesting potential applications in neurodegenerative disease.
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Size Unit Price Stock
10 mg €120.00 In Stock
50 mg €400.00 In Stock
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Size Unit Price Stock
2 x 10 mg €180.00 In Stock
2 x 50 mg €600.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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