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ML 324
- NCGC00183808
Axon 3562
CAS:
1222800-79-4
Purity:
98%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C21H23N3O2
- MW: 349.43
Description
Inhibitor of Jumonji domain-containing protein 2 (JMJD2, an "eraser") histone demethylase; effectively blocked herpes simplex virus (HSV) IE gene expression and prevented viral reactivation from latency; >75 fold more efficient than DMOG. ML 324 is also available as its HCl-salt (Axon 2081).
More Information
| Parent CAS No. | 1222800-79-4 |
|---|---|
| Chemical Name | N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide |
| SMILES | C1N=C2C(O)=CC(C3C=CC(C(NCCCN(C)C)=O)=CC=3)=CC2=CC=1 |
| MFCD | MFCD28053518 |
| InChi | InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26) |
| InChiKey | QDBVSOZTVKXUES-UHFFFAOYSA-N |
| CID | 44143209 |
| Short Description | JMJD2 inhibitor |
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