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AdipoRon

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2275

CAS [924416-43-3]

MF C27H28N2O3
MW 428.52

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

AdipoRon

Description

Orally active small-molecule AdipoR agonist (Kd values 1.8 and 3.1 μM for AdipoR1 and AdipoR2 respectively) that exerts antidiabetic effects via activation of AMPK and PPAR-α pathways.AdipoRon ameliorated insulin resistance, glucose intolerance, and diabetes of genetically obese rodent model db/db mice, thereby prolonging the shortened lifespan of db/db mice on a high-fat diet.
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Size Unit Price Stock
10 mg €80.00 In Stock
50 mg €240.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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