Thioridazine hydrochloride

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2193

CAS [130-61-0]

MF C21H26N2S2.HCl
MW 407.04

  • Purity: 99%
  • Soluble in water and DMSO

Thioridazine hydrochloride

Description

Antipsychotic with (sub-) nanomolar affinity for dopamine and α-adrenergic receptors (Ki of 0.4 nM, 1.5 nM, 1.5 nM, 3.2 nM, 2.4 nM for D2, D3, D4, α1A, and α1B resp.).

Recently, Thioridazine was found to inhibit full length recombinant MALT1 (IC50 3.43 μM). It inhibits anti-apoptotic NF-κB signaling and elicits toxic effects selectively on MALT1-dependent ABC-DLBCL cells. Additionally, it suppresses tumor growth activity by targeting the PI3K/Akt/mTOR/p70S6K signaling pathway.

Order
Size Unit Price Stock
10 mg €50.00 In Stock
50 mg €105.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...