Bulk Inquiry
Mitapivat
- PKM2 activator 1020
Axon 2149
CAS:
1260075-17-9
Purity:
99%
- Soluble in DMSO
- MF: C24H26N4O3S
- MW: 450.55
Description
Activator of pyruvate kinase isoenzyme M2 (PKM2), an enzyme involved in glycolysis. Since all tumor cells exclusively express the embryonic M2 isoform of PK, it is hypothesized that PKM2 is a potential target for cancer therapy. Modulation of PKM2 might also be effective in the treatment of obesity, diabetes, autoimmune conditions, and antiproliferation-dependent diseases.
More Information
| Parent CAS No. | 1260075-17-9 |
|---|---|
| Chemical Name | N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide |
| SMILES | C1(C(N2CCN(CC3CC3)CC2)=O)C=CC(NS(C2C3N=CC=CC=3C=CC=2)(=O)=O)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C24H26N4O3S/c29-24(28-15-13-27(14-16-28)17-18-6-7-18)20-8-10-21(11-9-20)26-32(30,31)22-5-1-3-19-4-2-12-25-23(19)22/h1-5,8-12,18,26H,6-7,13-17H2 |
| InChiKey | XAYGBKHKBBXDAK-UHFFFAOYSA-N |
| CID | 59634741 |
| Short Description | PKM2 activator |
Other Categories
Get a Quote for
Loading...