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Bazedoxifene acetate
- TSE424 - Viviant
- Parent CAS: 198481-32-2
- Soluble in DMSO
- MF: C30H34N2O3.C2H4O2
- MW: 530.65
Description
Third generation selective estrogen receptor modulator (SERM).
This product is also available as Bazedoxifene hydrochloride (Axon 1748).
More Information
| Parent CAS No. | 198481-32-2 |
|---|---|
| Chemical Name | 1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate |
| extra_info | . |
| SMILES | N1(CC2=CC=C(OCCN3CCCCCC3)C=C2)C2=C(C=C(O)C=C2)C(C)=C1C1=CC=C(O)C=C1.C(O)(=O)C |
| MFCD | MFCD09260074 |
| InChi | InChI=1S/C30H34N2O3.C2H4O2/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31;1-2(3)4/h6-15,20,33-34H,2-5,16-19,21H2,1H3;1H3,(H,3,4) |
| InChiKey | OMZAMQFQZMUNTP-UHFFFAOYSA-N |
| CID | 154256 |
| Short Description | SERM |
References
- BS Komm et al. Bazedoxifene Acetate: A Selective Estrogen Receptor Modulator with Improved Selectivity. Endocrinology 2005, 146(9), 3999-4008.
- DM Biskobing et al. Update on bazedoxifene: A novel selective estrogen receptor modulator. Clin. interv. Aging. 2007, 2(3), 299–303.
- SL Silverman et al. Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled (...). J. Bone Mineral Res. 2008, 23(12), 1923–1934.
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