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Bazedoxifene hydrochloride
- WAY 140424 - TSE 424 hydrochloride- Parent CAS: 198481-32-2
- Soluble in DMSO
- MF: C30H34N2O3.HCl
- MW: 507.06
Description
Third generation selective estrogen receptor modulator (SERM).
This product is also available as its acetate salt (Axon 2051)
More Information
| Parent CAS No. | 198481-32-2 |
|---|---|
| Chemical Name | 1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol hydrochloride |
| extra_info | . |
| SMILES | C1(O)C=C2C(C)=C(C3C=CC(O)=CC=3)N(CC3C=CC(OCCN4CCCCCC4)=CC=3)C2=CC=1.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C30H34N2O3.ClH/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31;/h6-15,20,33-34H,2-5,16-19,21H2,1H3;1H |
| InChiKey | COOWZQXURKSOKE-UHFFFAOYSA-N |
| CID | 9936012 |
| Short Description | SERM |
References
- DM Biskobing et al. Update on bazedoxifene: A novel selective estrogen receptor modulator. Clin. interv. Aging. 2007, 2(3), 299–303.
- SL Silverman et al. Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, (...) J. Bone Mineral Res. 2008, 23(12), 1923–1934.
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