PCI 32765 - Ibrutinib

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1858

CAS [936563-96-1]

MF C25H24N6O2
MW 440.50

  • Purity: 99%
  • Soluble in DMSO

PCI 32765

Description

Orally bioavailable and highly selective inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity; inhibiting BTK activity, B-cell-mediated signaling and the growth of malignant B cells that overexpress BTK; an experimental drug candidate for chronic lymphocytic leukemia (CLL), mantle cell lymphoma, diffuse large B-cell lymphoma, and multiple myeloma etcBTK, a member of the BTK/Tec family of non-recetor cytoplasmic tyrosine kinases, is required for B cell receptor (BCR) signaling, plays a key role in B-cell maturation, and is overexpressed in a number of B-cell malignancies
Order
Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €350.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €520.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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