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LFM-A13
Axon 2862
CAS:
244240-24-2
Purity:
99%
- Soluble in DMSO
- MF: C11H8Br2N2O2
- MW: 360
Description
LFM-A13 is a potent and specific inhibitor of BTK (IC50 value of 2.5 µM). LFM-A13 did not affect the enzymatic activity of other protein tyrosine kinases, including Janus kinases JAK1 and JAK2, Src family kinase HCK, and receptor family tyrosine kinases E.
More Information
| Parent CAS No. | 244240-24-2 |
|---|---|
| Chemical Name | (Z)-2-Cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide |
| SMILES | C/C(/O)=C(C#N)/C(=O)NC1C=C(Br)C=CC=1Br |
| MFCD | MFCD09878279 |
| InChi | InChI=1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6- |
| InChiKey | UVSVTDVJQAJIFG-VURMDHGXSA-N |
| CID | 54676905 |
| Short Description | BTK inhibitor |
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