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Rupintrivir - AG7088

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1571

CAS [223537-30-2]

MF C31H39FN4O7
MW 598.66

Purity: 98%
Optical purity: Optically pure
Soluble in DMSO

Rupintrivir

Description

An irreversible human rhinovirus (HRV) 3C protease inhibitor

G Witherell. AG-7088 Pfizer. Curr. Opin. Investig. Drugs. 2000, 1(3), 297-302.

AG-7088. Drugs Fut. 2000, 25, 1, 9

ST Worland et al. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J. Med. Chem. 1999, 42,(7), 1203.

SL Binford et al. In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease. ANTIMICROB. AGENTS CHEMOTHER. 2007, 51(12), 4366–4373.

Immunology HRV3C Protease EC 3.4.22.28 Antiviral agents Infectious Disease

HRV3C protease inhibitor

Chemical name

(E)-(S)-4-{(2R,5S)-2-(4-Fluoro-benzyl)-6-methyl-5-[(5-methyl-isoxazole-3-carbonyl)-amino]-4-oxo-heptanoylamino}-5-((S)-2-oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester

Parent CAS No.

[223537-30-2]

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1 mg	€80.00	In Stock
5 mg	€180.00	In Stock
25 mg	€720.00	In Stock

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