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RO 60-0175
- Parent CAS: 169675-08-5
- Optical Purity: >98% e.e.
- Soluble in DMSO
- MF: C11H12ClFN2.C4H4O4
- MW: 342.75
Description
More Information
| Parent CAS No. | 169675-08-5 |
|---|---|
| Chemical Name | (S)-2-(6-Chloro-5-fluoro-indol-1-yl)-1-methyl-ethylamine fumarate |
| SMILES | C(=C/C(=O)O)C(=O)O.N1(C[C@H](C)N)C=CC2C=C(F)C(Cl)=CC1=2 |&1:10,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C11H12ClFN2.C4H4O4/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15;5-3(6)1-2-4(7)8/h2-5,7H,6,14H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t7-;/m0./s1 |
| InChiKey | CEPHEXXZGQBXGT-XZTIXWOLSA-N |
| CID | 6446435 |
| Short Description | 5-HT2C agonist |
References
- Damjanoska et al. Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonist. J. Pharmacol. Exp. Ther. 2003, 304,1209.
- Kennett et al. Effects of Ro 60-0175, a 5-HT2C receptor agonist, in three animal models of anxiety. Eur. J. Pharmacol. 2000, 387, 197.
- Martin et al. 5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential. J. Pharmacol. Exp. Ther. 1998, 286, 913.
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