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Tilfrinib
- Soluble in DMSO and EtOH
- MF: C17H13N3O
- MW: 275.3
Description
Potent Brk inhibitor (breast tumor kinase; IC50 values 3.15 nM) with antiproliferative activity in various breast tumor cell lines. Brk is also known as protein tyrosine kinase 6 (PTK6).
More Information
| Parent CAS No. | 1600515-49-8 |
|---|---|
| Chemical Name | 3-(9H-pyrido[2,3-b]indol-4-ylamino)phenol |
| SMILES | C1(O)=CC=CC(NC2=C3C4=C(NC3=NC=C2)C=CC=C4)=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C17H13N3O/c21-12-5-3-4-11(10-12)19-15-8-9-18-17-16(15)13-6-1-2-7-14(13)20-17/h1-10,21H,(H2,18,19,20) |
| InChiKey | RXPZOSHFGJWSLQ-UHFFFAOYSA-N |
| CID | 76332983 |
| Short Description | Brk inhibitor |
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