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SF 1670
- Soluble in DMSO
- MF: C19H17NO3
- MW: 307.34
Description
More Information
| Parent CAS No. | 345630-40-2 |
|---|---|
| Chemical Name | N-(9,10-dioxo-9,10-dihydrophenanthren-2-yl)pivalamide |
| SMILES | C(NC1=CC=C2C(=C1)C(=O)C(=O)C1=C2C=CC=C1)(=O)C(C)(C)C |
| MFCD | N.A. |
| InChi | InChI=1S/C19H17NO3/c1-19(2,3)18(23)20-11-8-9-13-12-6-4-5-7-14(12)16(21)17(22)15(13)10-11/h4-10H,1-3H3,(H,20,23) |
| InChiKey | VZQDDSYKVYARDW-UHFFFAOYSA-N |
| CID | 9926586 |
| Short Description | PTEN inhibitor |
References
- Y. Li et al. Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. Blood. 2011, 117, 6702-6713.
- R.A. Urbanek et al. Potent reversible inhibitors of the protein tyrosine phosphatase CD45. J. Med. Chem. 2001, 44, 1777-1793.
- E. Rosivatz et al. A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN). ACS Chem. Biol. 2006, 1, 780-790.
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