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ISX9
- Isoxazole 9
- Soluble in DMSO and EtOH
- MF: C11H10N2O2S
- MW: 234.27
Description
ISX9 is an agonist of the Wnt/β-catenin pathway by potentiating the association between LRP6 and Axin1. Moreover, ISX9 is a neurogenesis-promoting small molecule compound that can up-regulate the expression of NeuroD1 and induce differentiation of neuronal, cardiac and islet endocrine progenitors.
More Information
| Parent CAS No. | 832115-62-5 |
|---|---|
| Chemical Name | N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide |
| SMILES | C1(C=C(C2SC=CC=2)ON=1)C(=O)NC1CC1 |
| MFCD | MFCD04133937 |
| InChi | InChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14) |
| InChiKey | SYENTKHGMVKGAQ-UHFFFAOYSA-N |
| CID | 19582717 |
| Short Description | Wnt agonist |
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