Bulk Inquiry
BVT 2733 hydrochloride
Axon 1756
- Parent CAS: 376640-41-4
Purity:
99%
- Soluble in DMSO
- MF: C17H21ClN4O3S2.HCl
- MW: 465.42
Description
Selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1
More Information
| Parent CAS No. | 376640-41-4 |
|---|---|
| Chemical Name | 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide hydrochloride |
| SMILES | C1(S(NC2=NC(CC(N3CCN(C)CC3)=O)=CS2)(=O)=O)=CC=CC(Cl)=C1C.Cl |
| MFCD | MFCD13152134 |
| InChi | InChI=1S/C17H21ClN4O3S2.ClH/c1-12-14(18)4-3-5-15(12)27(24,25)20-17-19-13(11-26-17)10-16(23)22-8-6-21(2)7-9-22;/h3-5,11H,6-10H2,1-2H3,(H,19,20);1H |
| InChiKey | VQQOVTXLJDVTLF-UHFFFAOYSA-N |
| CID | 6918650 |
| Short Description | 11β-HSD1 inhibitor |
References
- P Alberts et al. Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology. 2003, 144(11), 4755-4762.
- SJ Wang et al. Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice. Diabetologia. 2006, 49(6), 1333-7.
Other Categories
Get a Quote for
Loading...
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.