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Vorasidenib
- AG881
Axon 4024
CAS:
1644545-52-7
- Optical Purity: Optically pure
- Soluble in DMSO and EtOH
- MF: C14H13ClF6N6
- MW: 414.74
Description
Vorasidenib is a first-in-class, potent, orally active, brain-penetrant dual mIDH1/2 inhibitor with IC50 values of 6 nM and 12 nM for IDH1-R132H and IDH2-R140Q, respectively.
More Information
| Parent CAS No. | 1644545-52-7 |
|---|---|
| Chemical Name | 6-(6-Chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine |
| SMILES | C1C(C2N=C(N[C@H](C)C(F)(F)F)N=C(N[C@H](C)C(F)(F)F)N=2)=NC(Cl)=CC=1 |&1:6,15,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | IDH1/2 inhibitor |
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