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RSL3
- 1S,3R-RSL3
Axon 3611
CAS:
1219810-16-8
- Optical Purity: 99.6% d.e.
- Soluble in DMSO and EtOH
- MF: C23H21ClN2O5
- MW: 440.88
Description
RSL3 is a GPX4 inhibitor and ferroptosis inducer. RSL3 exhibited selective lethality against cells with HRASV12. A negative control (1R,3R)-RSL3 is available as Axon 3617.
More Information
| Parent CAS No. | 1219810-16-8 |
|---|---|
| Chemical Name | (1S,3R)-Methyl 2-(2-chloroacetyl)-1-(4-(methoxycarbonyl)phenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate |
| SMILES | C12C[C@H](C(=O)OC)N(C(CCl)=O)[C@@H](C3C=CC(C(=O)OC)=CC=3)C=1NC1C=CC=CC2=1 |&1:2,12,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10,18,21,25H,11-12H2,1-2H3/t18-,21+/m1/s1 |
| InChiKey | TXJZRSRTYPUYRW-NQIIRXRSSA-N |
| CID | 1750826 |
| Short Description | GPX4 inhibitor |
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