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Liproxstatin-1
Axon 2990
CAS:
950455-15-9
Purity:
98%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C19H21ClN4
- MW: 340.85
Description
Liproxstatin-1 is a potent ferroptosis inhibitor (IC50 value of 22 nM) which is able to suppress ferroptosis in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
More Information
| Parent CAS No. | 950455-15-9 |
|---|---|
| Chemical Name | N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine |
| SMILES | C1C=C2NC3(CCNCC3)C(NCC3C=C(Cl)C=CC=3)=NC2=CC=1 |
| MFCD | MFCD14948691 |
| InChi | InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23) |
| InChiKey | YAFQFNOUYXZVPZ-UHFFFAOYSA-N |
| CID | 135735917 |
| Short Description | Ferroptosis inhibitor |
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