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UAMC-3203 trihydrochloride
- Parent CAS: 2271358-64-4
- Soluble in water and DMSO
- MF: C25H37N5O2S·3HCl
- MW: 581.04
Description
UAMC-3203 trihydrochloride is a potent ferroptosis inhibitor with an IC50 value of 12 nM. UAMC-3203 inhibits the production of reactive oxygen species (ROS) and lipid peroxides, preventing ferroptosis and reducing neuronal degeneration. Additionally, UAMC-3203 suppresses astrocyte proliferation and microglia/macrophage activation, as well as the release of ferroptosis-related inflammatory factors.
More Information
| Parent CAS No. | 2271358-64-4 |
|---|---|
| Chemical Name | 3-(Benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide trihydrochloride |
| SMILES | C1(NCC2=CC=CC=C2)=CC(S(=O)(=O)NCCN2CCNCC2)=CC=C1NC1CCCCC1.Cl.Cl.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C25H37N5O2S.3ClH/c31-33(32,28-15-18-30-16-13-26-14-17-30)23-11-12-24(29-22-9-5-2-6-10-22)25(19-23)27-20-21-7-3-1-4-8-21;;;/h1,3-4,7-8,11-12,19,22,26-29H,2,5-6,9-10,13-18,20H2;3*1H |
| InChiKey | LOXORAZUZLUZIK-UHFFFAOYSA-N |
| CID | 137701965 |
| Short Description | Ferroptosis inhibitor |
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