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Tenofovir alafenamide
- GS-7340
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C21H29N6O5P
- MW: 476.47
Description
Tenofovir alafenamide is an orally bioavailable, intracellular prodrug of Tenofovir (Axon 3157), which is a selective inhibitor of HIV-1 reverse transcriptase.
More Information
| Parent CAS No. | 379270-37-8 |
|---|---|
| Chemical Name | (S)-Isopropyl 2-((S)-(((R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methyl)(phenoxy)phosphorylamino)propanoate |
| SMILES | C12N=CN(C[C@H](OC[P@](OC3C=CC=CC=3)(N[C@@H](C)C(=O)OC(C)C)=O)C)C=1N=CN=C2N |&1:5,8,17,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1 |
| InChiKey | LDEKQSIMHVQZJK-CAQYMETFSA-N |
| CID | 9574768 |
| Short Description | HIV-1 RT inhibitor |
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