5-HT3

5-HT3 differ from all other 5-HT (serotonin) receptors whose actions are mediated via G proteins. Their structure and function has placed them in the Cys-loop family of cationic ligand-gated ion channels. 5-HT3 receptors are located in both the peripheral (PNS) and central (CNS) nervous systems. In the CNS, 5-HT3 receptors may play roles in a variety of functions including emesis, cognition and anxiety, whereas in the PNS they play a role in a variety of sympathetic, parasympathetic and sensory functions (e.g. signaling in gastrointestinal tract, gut motility and peristalsis)[1].


[1] 5-HT3 Receptors. A. J. Thompson, S. C. R. Lummis. Curr Pharm Des. 2006; 12(28): 3615–3630.

6 Item(s)

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Axon ID Name Description From price
1097 Alosetron hydrochloride 5-HT3 antagonist €85.00
1096 Azasetron hydrochloride 5-HT3 antagonist €90.00
2534 Azasetron hydrochloride, (+)- 5-HT3 antagonist €135.00
2535 Azasetron hydrochloride, (-)- 5-HT3 antagonist €135.00
1153 B-HT 920 dihydrochloride D2 agonist, α2 adrenoceptor agonist; 5-HT3 antagonist €75.00
1449 Granisetron hydrochloride 5-HT3 antagonist €85.00

6 Item(s)

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