Based on 8 reference(s) in Google Scholar 8 10 8

Axon 3695

CAS [1844849-10-0]

MF C22H24Cl2N2O5
MW 467.34

  • Purity: 99%
  • Optical purity: 99% e.e.
  • Soluble in DMSO



PF-06821497 (optically pure R-enantiomer) is a small molecule inhibitor of Histone Methyltransferase (HMT) EZH2, potently and selectively inhibiting the activities of both wild-type (Ki = 0.3nM) and mutant (Y641N) (Ki < 0.1nM).

KEYWORDS: PF-06821497 | Supplier | EZH2 HMTase inhibitor | PF06821497 | PF 06821497 | CT-PF0682 | CAS [1844849-10-0] | Histone | HMTase | Inhibitor | Enzymes

Inhibitor of Histone Lysine Methyltransferase EZH2

Chemical name


Source information

Sold in collaboration with Chemietek

Parent CAS No.


Size Unit Price Stock
2 mg €160.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...