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Propafenone hydrochloride
- Parent CAS: 54063-53-5
- Soluble in water, DMSO and EtOH
- MF: C21H27NO3.HCl
- MW: 377.9
Description
Propafenone hydrochloride is a multi-channel blocker and antiarrhythmic agent.
More Information
| Parent CAS No. | 54063-53-5 |
|---|---|
| Chemical Name | 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride |
| SMILES | C1C=C(OCC(CNCCC)O)C(C(=O)CCC2C=CC=CC=2)=CC=1.Cl |
| MFCD | MFCD00079243 |
| InChi | InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H |
| InChiKey | XWIHRGFIPXWGEF-UHFFFAOYSA-N |
| CID | 36708 |
| Short Description | Ca2+/K+/Na+ blocker |
References
- HJ Hapke et al. Zur Pharmakologie von 2'-[2-Hydroxy-3-(propylamino)-propoxy]-3-phenylpropiophenon (Propafenon, SA 79)-hydrochlorid [Pharmacology of 2'-[2-hydroxy-3-(propylamino)-propoxy]-3-phenylpropiophenone (Propafenone, SA 79)-hydrochloride]. Arzneimittelforschung. 1976;26(10):1849-57.
- F Pérez-Vizcaíno et al. Voltage- and time-dependent inhibitory effects on rat aortic and porcine coronary artery contraction induced by propafenone and quinidine. Br J Pharmacol. 1994 Dec;113(4):1281-8.
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