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LOXO-101 sulfate - Larotrectinib sulfate | ARRY-470

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3407

CAS [1223405-08-0]

MF C21H22F2N6O2.H2SO4
MW 526.51

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water and DMSO

LOXO-101 sulfate

Description

LOXO-101 sulfate is a first-in-class, potent, highly selective and ATP-competitive tropomyosin receptor kinase (TRK) inhibitor with IC50 values of 6.5 nM, 8.1 nM and 10.6 nM for TRKA, TRKB and TRKC, respectively.

KEYWORDS: LOXO-101 sulfate | supplier | TRK inhibitor | Larotrectinib sulfate | ARRY-470 | ARRY470 | ARRY 470 | CAS [1223405-08-0] | [1223403-58-4] | [1919868-83-9] | [1919868-87-3] | [1919868-85-1] | Neurotrophin | Trk | Inhibitor | Receptors | TRK fusion cancer

First-in-class, potent, highly selective and ATP-competitive TRK inhibitor

Chemical name

(S)-N-(5-((R)-2-(2,5-Difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate

Parent CAS No.

[1223403-58-4]

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Size Unit Price Stock
10 mg €80.00 In Stock
50 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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