Bulk Inquiry
PQ401
Axon 3341
CAS:
196868-63-0
Purity:
99%
- Soluble in DMSO
- MF: C18H16ClN3O2
- MW: 341.79
Description
PQ401 is a potent inhibitor of IGF-IR signalling. PQ401 inhibited autophosphorylation of the IGF-IR in cultured human MCF-7 cells with an IC50 value of 12 μM and autophosphorylation of the isolated kinase domain of the IGF-IR with an IC50 value of <1 μM.
More Information
| Parent CAS No. | 196868-63-0 |
|---|---|
| Chemical Name | 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea |
| SMILES | C12C=CC=CC1=C(NC(=O)NC1C(OC)=CC=C(Cl)C=1)C=C(C)N=2 |
| MFCD | MFCD00160558 |
| InChi | InChI=1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23) |
| InChiKey | YBLWOZUPHDKFOT-UHFFFAOYSA-N |
| CID | 9549305 |
| Short Description | IGF1R inhibitor |
Other Categories
Get a Quote for
Loading...
Are you sure you would like to remove this item from the shopping cart?
This item is a part of the approved quote. Removing it will remove all quote items from the cart.