Emtricitabine - (-)-FTC

Based on 3517 reference(s) in Google Scholar 8 10 3517

Axon 3305

CAS [143491-57-0]

MF C8H10FN3O3S
MW 247.25

Purity: 100%
Optical purity: Optically pure
Soluble in water and DMSO

Emtricitabine

Description

Emtricitabine is a potent, orally bioavailable nucleoside reverse transcriptase inhibitor (NRTI) with an apparent IC50 value of 10 nM.

KEYWORDS: Emtricitabine | supplier | NRT inhibitor | (-)-FTC | CAS [143491-57-0] | [258832-61-0] | DNA-RNA | RT | Inhibitor | Enzymes | Emtriva | HIV

PA Furman et al. The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. Antimicrob Agents Chemother. 1992 Dec;36(12):2686-92.

JE Frampton et al. Emtricitabine: a review of its use in the management of HIV infection. Drugs. 2005;65(10):1427-48.

Immunology Miscellaneous RT EC 2.7.7.49

Potent and orally bioavailable NRT inhibitor (HIV-1)

Chemical name

4-Amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one

Parent CAS No.

[143491-57-0]

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Emtricitabine - (-)-FTC

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Emtricitabine - (-)-FTC

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