dCeMM2

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3293

CAS [296771-07-8]

MF Soluble in DMSO
MW 370.82

  • Purity: 99%
  • Soluble in DMSO

dCeMM2

Description

dCeMM2 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12:cyclin K with a CRL4B ligase complex. The pronounced destabilization of cyclin K by dCeMM2 occurred alongside a milder destabilization of both associated kinases CDK12 and CDK13.

KEYWORDS: dCeMM2 | supplier | Glue degrader | CAS [296771-07-8] | Protein degradation | Ubiquitin Ligase (E3; other) | Degrader | Enzymes | Molecular glue degrader

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10 mg €95.00 In Stock
50 mg €380.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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