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MG degrader compound E14
Axon 4143
CAS:
N.A.
Purity:
98%
- Soluble in DMSO and EtOH
- MF: C31H37N5O7
- MW: 591.65
Description
MG degrader compound E14 is a potent molecular glue (MG) degrader targeting IKZF1/3, GSPT1 and 2 with profound effects on a panel of cancer cells (EC50 values of 11.08 nM and 1.485 nM in MM.1S and NCI-H929 cells, respectively).
More Information
| Parent CAS No. | N.A. |
|---|---|
| Chemical Name | N-(4-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-ylamino)butyl)-2-(N-isobutylformamido)-2-(3-methoxyphenyl)acetamide |
| MFCD | N.A. |
| Short Description | MG degrader |
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