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NVP-DKY709
Axon 3297
CAS:
2291360-73-9
Purity:
99%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C25H27N3O3
- MW: 417.5
Description
NVP-DKY709 is a first-in-class selective CRBN glue degrader of IKZF2 that spares IKZF1/3. In vivo, treatment with NVP-DKY709 delayed tumor growth in mice with a humanized immune system and enhanced immunization responses in cynomolgus monkeys.
More Information
| Parent CAS No. | 2291360-73-9 |
|---|---|
| Chemical Name | 3-(5-(1-Benzylpiperidin-4-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione |
| MFCD | N.A. |
| Short Description | IKZF2 degrader |
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