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Axon 3271
CAS [1788055-11-7]
MF C25H28N4O3MW 432.51
VU0486846 is a potent and highly selective M1 PAM (EC50 value of 0.31 μM, 85%), devoid of agonist activity in the PFC, as well as cholinergic or other adverse effects in mice, rats and NHP, which results in robust procognitive activity in rodent models.
KEYWORDS: VU0486846 | supplier | M1 PAM | VU 0486846 | VU-0486846 | CAS [1788055-11-7] | Acetylcholine | CHRM1 | PAM | Receptors | Schizophrenia
(R)-4-(4-(1H-Pyrazol-1-yl)benzyl)-N-((1S,2S)-2-hydroxycyclohexyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide
[1788055-11-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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