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A 381393
Axon 2944
CAS:
726174-00-1
Purity:
99%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C20H24N4
- MW: 320.43
Description
Potent, brain-penetrant, selective antagonist of the dopamine D4 receptor with both in vitro and in vivo activity (Ki value of 1.5 nM). A 381393 lacks any significant intrinsic agonist activity.
More Information
| Parent CAS No. | 726174-00-1 |
|---|---|
| Chemical Name | 2-((4-(3,4-Dimethylphenyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole |
| SMILES | C1CN(C2C=CC(C)=C(C)C=2)CCN1CC1NC2C=CC=CC=2N=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C20H24N4/c1-15-7-8-17(13-16(15)2)24-11-9-23(10-12-24)14-20-21-18-5-3-4-6-19(18)22-20/h3-8,13H,9-12,14H2,1-2H3,(H,21,22) |
| InChiKey | SAQMCVDGOIRQTC-UHFFFAOYSA-N |
| CID | 11301655 |
| Short Description | D4 antagonist |
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