ML 355

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 2873

CAS [1532593-30-8]

MF C21H19N3O4S2
MW 441.52

  • Purity: 98%
  • Soluble in DMSO

ML 355

Description

Potent inhibitor of 12-lipoxygenase (12-LOX) (IC50 value of 0.34 µM) which shows excellent selectivity against related enzymes (15-LOX-1, 5-LOX, 15-LOX-2, COX-1/-2). Besides, ML 355 exhibits a favourable in vitro ADME and in vivo PK profile with activity in disease relevant cell-based systems, such thrombosis (platelet aggregation and calcium mobilization), and diabetes (12-HETE reducing in β -cells).

KEYWORDS: ML 355 | supplier | Lipoxygenase inhibitor | ML355 | ML-355 | CAS [1532593-30-8] | Fatty acid (Arachidonic acid) | LOX | Inhibitor | Enzymes | Thrombosis | Diabetes

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €325.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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