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Axon 2845
CAS [1513879-19-0]
MF C22H18ClN5O2MW 419.86
KDU691 is a plasmodium PI4K inhibitor (IC50 values of 0.18 μM and 0.061 μM against hypnozoite forms and liver schizontsm, respectively) which selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites. Moreover, KDU691 was fully protective when administered in vivo as causal prophylactic and radical-cure agents for Plasmodium cynomolgi sporozoite-infected rhesus macaques.
KEYWORDS: KDU691 | supplier | PI4K inhibitor | KDU-691 | KDU 691 | CAS [1513879-19-0] | Phosphatidylinositol | PI4K | Inhibitor | Enzymes | Plasmodium
N-(4-Chlorophenyl)-N-methyl-3-(4-(methylcarbamoyl)phenyl)imidazo[1,2-a]pyrazine-6-carboxamide
[1513879-19-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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