Bulk Inquiry
CHMFL-PI4K-127
Axon 4336
CAS:
2377604-81-2
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C18H15ClN4O3S
- MW: 402.86
Description
CHMFL-PI4K-127 is a potent, highly selective and orally bioavailable PfPI4K inhibitor with an IC50 value of 0.9 nM. CHMFL-PI4K-127 shows potent antimalarial activity against both blood and liver stages of Plasmodium.
More Information
| Parent CAS No. | 2377604-81-2 |
|---|---|
| Chemical Name | N-Methyl-6'-chloro-5'-(phenylsulfonylamino)[3,3'-bipyridyl]-5-carboxamide |
| SMILES | C1=C(C2=CN=CC(C(=O)NC)=C2)C=NC(Cl)=C1NS(=O)(=O)C1=CC=CC=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H15ClN4O3S/c1-20-18(24)14-7-12(9-21-10-14)13-8-16(17(19)22-11-13)23-27(25,26)15-5-3-2-4-6-15/h2-11,23H,1H3,(H,20,24) |
| InChiKey | IHWSJFBJORCEAK-UHFFFAOYSA-N |
| CID | 141754964 |
| Short Description | PI(4)K inhibitor |
Other Categories
Get a Quote for
Loading...