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UCB9608
Axon 3005
CAS:
1616413-96-7
- Optical Purity: 99% e.e.
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C20H26N8O2
- MW: 410.47
Description
UCB9608 is a potent and orally bioavailable PI4KIIIβ inhibitor (IC50 value of 11 nM) that inhibits the HuMLR response with an IC50 value of 37 nM. The potency and excellent ADME properties of UCB9608 make it an ideal compound for future use as an in vitro and in vivo probe to elucidate the emerging role of PI4KIII β inhibition in immune processes.
More Information
| Parent CAS No. | 1616413-96-7 |
|---|---|
| Chemical Name | (S)-4-(6-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methylphenyl)-3-methylpiperazine-1-carboxamide |
| SMILES | C1(NC(N2CCN(C3C4C=NN(C)C=4N=C(N)N=3)[C@@H](C)C2)=O)C(C)=CC(OC)=CC=1 |&1:18,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1 |
| InChiKey | WRONAJQPZWDYAR-ZDUSSCGKSA-N |
| CID | 76282073 |
| Short Description | PI4KIIIβ inhibitor |
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