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Axon 2841
CAS [1039455-84-9]
MF C19H22N6SMW 366.48
COTI-2 is an anti-cancer drug which appears to act both by reactivating mutant p53 and inhibiting the PI3K/AKT/mTOR pathway. Proposed to cause cancer cell death via apoptosis. COTI-2 exhibits potent anti-proliferative activity against a wide variety of human cancer cell lines in vitro (at nanomolar concentrations) and against human tumor xenografts.
KEYWORDS: COTI-2 | supplier | p53 activator | COTI2 | COTI 2 | CAS [1039455-84-9] | DNA-RNA | p53 | Activator | Transcription Factors
N'-(6,7-Dihydroquinolin-8(5H)-ylidene)-4-(pyridin-2-yl)piperazine-1-carbothiohydrazide
[1039455-84-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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