HS666 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2781

CAS [1409931-99-2]

MW 331.88

  • Purity: 99%
  • Soluble in DMSO

HS666 hydrochloride


HS666 is a selective κ opioid receptor partial agonist (Ki value of 5.9 nM) which activates central κ receptors to produce potent antinociception. Moreover, HS666 displays pharmacological characteristics of a κ receptor analgesic with reduced liability for aversive effects correlating with its low efficacy in the β-arrestin2 signalling pathway.

Keywords: HS666 hydrochloride | supplier | Kappa-opioid partial agonist | HS 666 hydrochloride | HS-666 hydrochloride | CAS [1409931-99-2] | [1409931-91-4] | Opioids | OPR-κ | Partial agonist | Receptors | Antinociception

Size Unit Price Stock
5 mg €135.00 In Stock
25 mg €475.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €200.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...