Metabolite of Tamoxifen and a selective estrogen receptor modulator (SERM); Potently inhibits the growth of estrogen-stimulated BT474 cells (IC50: 54 nM). Approximately 100-fold more potent as an antagonist of the ERα than the parent drug. Drug for the treatment of estrogen receptor (ER) positive breast cancer.
Hydrochloride salt of Endoxifen (Axon 2190) which dissolves readily in water and aqueous media.
KEYWORDS: Endoxifen hydrochloride | supplier | Endoxifen | SERM | CAS [1197194-41-4] | [110025-28-0] | Estrogen | Selective Estrogen Receptor (ER) Modulator | Nuclear receptor | metabolite | ER positive breast cancer | Tamoxifen