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RIPA-56
Axon 2677
CAS:
1956370-21-0
Purity:
99%
- Soluble in DMSO
- MF: C13H19NO2
- MW: 221.3
Description
Highly potent, selective, and metabolically stable inhibitor of receptor-interacting protein 1 (RIP1; IC50 value 13 nM) for the treatment of systemic inflammatory response syndrome (SIRS). RIPA-56 efficiently reduced TNFα-induced mortality and multiorgan damage.
More Information
| Parent CAS No. | 1956370-21-0 |
|---|---|
| Chemical Name | N-benzyl-N-hydroxy-2,2-dimethylbutanamide |
| SMILES | C(N(O)CC1=CC=CC=C1)(=O)C(C)(C)CC |
| MFCD | N.A. |
| InChi | InChI=1S/C13H19NO2/c1-4-13(2,3)12(15)14(16)10-11-8-6-5-7-9-11/h5-9,16H,4,10H2,1-3H3 |
| InChiKey | AVYVHIKSFXVDBG-UHFFFAOYSA-N |
| CID | 121439991 |
| Short Description | RIP1 inhibitor |
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