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GSK'872
- GSK2399872A
Axon 3024
CAS:
1346546-69-7
Purity:
98%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C19H17N3O2S2
- MW: 383.49
Description
GSK’872 is a potent and selective RIP3 kinase inhibitor with an IC50 value of 1.8 nM for RIP3 kinase binding and an IC50 value of 1.3 nM for inhibition of kinase activity.
More Information
| Parent CAS No. | 1346546-69-7 |
|---|---|
| Chemical Name | N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine |
| SMILES | C1(S(=O)(=O)C(C)C)C=C2C(NC3C=CC4SC=NC=4C=3)=CC=NC2=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22) |
| InChiKey | ZCDBTQNFAPKACC-UHFFFAOYSA-N |
| CID | 54674134 |
| Short Description | RIP3 inhibitor |
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