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GSK'872

 - GSK2399872A
Axon 3024
CAS:  1346546-69-7
Purity:  98%
  • Soluble in 0.1N HCl(aq) and DMSO
  • MF:  C19H17N3O2S2
  • MW:  383.49

Description

GSK’872 is a potent and selective RIP3 kinase inhibitor with an IC50 value of 1.8 nM for RIP3 kinase binding and an IC50 value of 1.3 nM for inhibition of kinase activity.

More Information

Parent CAS No. 1346546-69-7
Chemical Name N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine
SMILES C1(S(=O)(=O)C(C)C)C=C2C(NC3C=CC4SC=NC=4C=3)=CC=NC2=CC=1
MFCD N.A.
InChi InChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22)
InChiKey ZCDBTQNFAPKACC-UHFFFAOYSA-N
CID 54674134
Short Description RIP3 inhibitor

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